Edel-Stem Rejuvenation Cream
A nourishing Swiss cream powered by edelweiss plant stem cells, for smoother, more youthful-looking skin.
- Smoother, more youthful-looking skinEdelweiss plant stem cells (Alpine callus culture)
- Rich, lasting nourishmentShea, avocado, and sunflower oils
- Revitalized, healthy-looking radianceMagnesium, zinc and copper mineral complex
- Antioxidant comfortVitamin E on a Swiss formula
- Complimentary Lèvres d’Or Golden Lip Mask on orders over $300Full size, worth $70. Added to your bag automatically once your order passes $300.
Made in Switzerland
Complimentary express delivery
The evening cream for skin in transition: density, comfort and resilience, restored overnight.
- TextureA rich, cushioning cream that absorbs fully and leaves no residue by morning.
- How to applyWarm a pearl-sized amount between the hands, then press into face, neck and décolleté in upward sweeps. Never rub. Avoid the immediate eye area.
- WhenEvening, over Youth Collagen Serum. Morning too for very dry skin, finished with a broad-spectrum SPF.
- Complete the ritualPairs with Youth Collagen Serum.
- Edelweiss plant stem cellsProtect against the oxidative stress that thins and dulls skin, supporting a denser, smoother, more resilient-looking surface.
- Shea, avocado and sunflower oilsRebuild the lipid layer that mature skin loses, easing dryness and leaving skin comfortable and supple by morning.
- Mineral complexZinc, magnesium and copper revitalise tired skin and restore a healthy-looking radiance.
- Panthenol (pro-vitamin B5)Soothes, softens and helps repair the feeling of dry, irritated skin.
- Vitamin EProtects the formula and the skin against oxidative stress through the night.
- Biosaccharide gum-1Forms a light moisture-holding veil for a second-skin softness that lasts.
Aqua, Caprylic/Capric Triglyceride, Glycerin, C12-15 Alkyl Benzoate, Cetearyl Alcohol, Butyrospermum Parkii Butter, Phenoxyethanol, Potassium Cetyl Phosphate, Cetearyl Glucoside, Carbomer, Persea Gratissima Oil, Sodium Benzoate, Tocopheryl Acetate, Tocopherol, Biosaccharide Gum-1, Ethylhexylglycerin, Sodium Hydroxide, Panthenol, Helianthus Annuus Seed Oil, Leontopodium Alpinum Callus Culture Extract, Citric Acid, Xanthan Gum, Zinc Gluconate, Magnesium Aspartate, Copper Gluconate
Edel-Stem Rejuvenation Cream is formulated and made in Switzerland, in the canton where the world’s most respected luxury skincare houses formulate.
- StandardProduced under Swiss cosmetic manufacturing regulation, batch by batch, with every ingredient disclosed.
- DevelopmentEdelweiss plant stem cells and three plant lipids in a cushioning texture developed for skin that has become drier and thinner.
- ProvenanceSwitzerland is consistently ranked among the top three countries in the world for skincare provenance.
- TestingCruelty-free. Never tested on animals.
- DeliveryComplimentary express shipping on every US order, delivered in 2–4 business days. Customs and duties included.
- ReturnsUnopened products in their original sealed packaging may be returned within 30 days of delivery. For hygiene and safety reasons we cannot accept returns of opened products. Damaged or defective items are replaced or refunded. Return shipping is paid by the customer; refunds are issued within 7 business days of receipt.
- QuestionsOur team replies within one business day.
Two minutes, eight questions, and we compose the ritual for your decade and your skin, with the set savings shown.
Alpine Cellular Matrix™
Powered by Alpine Cellular Matrix™ — a proprietary Swiss formulation of edelweiss callus extract, a magnesium, zinc and copper mineral complex, Provitamin B5, Grade A shea butter, and stable Vitamin E — backed by four years of Swiss laboratory development in a canton long synonymous with cellular cosmetic research.
Edelweiss Stem Cell Extract (Leontopodium Alpinum Callus Culture)
Alpine plant stem cell extract with antioxidant power, supporting the look of firm, smooth skin.
Revitalizing Mineral Trio (Magnesium, Zinc, Copper)
A mineral complex that helps revive the look of tired, dull skin.
Panthenol (Provitamin B5)
Deeply hydrates and soothes for lasting comfort.
Shea Butter
Restores surface lipids and comforts dry skin.
Avocado and Sunflower Seed Oils
Nourishing plant lipids that leave skin supple.
Biosaccharide Gum-1
Forms a soft moisture veil that smooths and comforts.
Vitamin E in two forms (Tocopheryl Acetate and Tocopherol)
Antioxidant defense for the skin barrier.
What this cream doesn’t do.
Does not sit on the surface or feel heavy.
The whipped-cloud texture is the discipline of the formulation, not an accident. Shea butter melts into the skin on contact — absorbing into a luminous, never-greasy finish that sits comfortably under makeup, SPF, or pillow. No silicone occlusion. No film-former tackiness.
Safe for twice-daily use, even on perimenopausal skin.
Compatible with retinoids, vitamin C, and peptide serums layered beneath — many users report less irritation from their actives after switching. Suitable for daily indefinite use.
Continue the ritual
View ritual sets
Glacial Toner
Apply before the serum. Swiss glacial minerals calibrate pH and open the absorption pathway for everything that follows in the ritual.
Youth Collagen Serum
Apply directly before Edel-Stem. The Palmitoyl Tripeptide-5 peptide complex and the Edelweiss cream are designed as a pair — the complete Youth Stem Cells Ritual.
Magic Glow Eye Cream
Apply on the orbital area before Edel-Stem covers the rest. Edelweiss and Vitamin C for the thinnest skin on the face.
What customers are saying
Everything you might wonder
about the sealing step.
Edel-Stem is formulated for both. The whipped-cloud texture absorbs into a luminous, never-greasy finish that sits beautifully under SPF and makeup in the morning, and provides rich overnight nourishment in the evening. Twice-daily use is the standard protocol.
If your skin is particularly oily during the day, you may prefer a lighter morning application and a richer evening one.
Yes — this is precisely what Edel-Stem is designed for. The Provitamin B5 and shea butter buffer the irritation that retinoids and acids can cause, while the Edelweiss antioxidant complex complements what vitamin C is doing. Many users report less stinging and visible peeling from their actives after switching to Edel-Stem.
For prescription tretinoin specifically, apply Edel-Stem either as a buffer underneath or as the moisturiser layered on top after the retinoid has fully absorbed.
Yes. Edel-Stem was formulated specifically with reactive and barrier-compromised skin in mind. It is alcohol-free and sulphate-free.
If you have a clinically diagnosed condition, always defer to your dermatologist’s specific guidance before introducing any new product.
No. Despite the rich whipped-cloud feel out of the jar, Edel-Stem absorbs completely within 60–90 seconds into a luminous, never-greasy finish that sits comfortably under SPF and makeup. The shea butter melts into the skin rather than sitting on top — no silicone occlusion, no film-former tackiness, no makeup pilling.
Allow two minutes for full absorption before applying SPF in the morning.
The most honest answer is: similar Swiss formulation discipline, transparent ingredient disclosure, and a fraction of the price of comparable heritage-luxury creams. Edel-Stem is built around seven actives — Edelweiss leontopodic acid, a magnesium, zinc and copper mineral complex, D-Panthenol, shea butter, avocado and sunflower seed oils, Biosaccharide Gum-1, and stable Vitamin E.
SÉRÈNE Suisse discloses every active and the actual ingredient research behind every claim. SÉRÈNE is priced at the architecture, not at the label.
The 50 ml jar is calibrated for one user, twice-daily application, lasting approximately six to eight weeks.
Unopened products in their original sealed packaging may be returned within 30 days of delivery. For hygiene and safety reasons we cannot accept returns of opened products. Damaged or defective items are replaced or refunded. Return shipping is paid by the customer; refunds are issued within 7 business days of receipt.
Complimentary express delivery. Unopened returns within 30 days.
Every US order ships express, 2–4 business days. Unopened products in their original sealed packaging may be returned within 30 days of delivery; for hygiene and safety reasons opened products cannot be returned. Return shipping is paid by the customer.
Not certain which ritual is
right for your skin?
Eight questions for the quiz, or write to our skin team and we reply within one business day.
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This is my new obsession! 💎
From the cleanser to the toner, serum, and rejuvenation cream — it completely transformed my skincare routine from simple to super-luxury. My skin has never felt this soft, radiant, and refined.
Absolutely in love — I’ll keep buying it again and again! ✨
Thank you. We’re honored to be part of your skincare ritual.
Works amazing
I’ve been testing these three for a while, and here’s my straight-to-the-point take.
Eye Cream, immediate “mirror results”
This is the best eye cream I’ve ever used. The moment I tap it in, I genuinely see a smoother, fresher eye area. Hydration is intense without heaviness, and it noticeably boosts elasticity so fine lines look softer right away and better over time.
Lip Mask, UAE-climate saver
My lips are usually wrecked by the dry A/C and heat here, and this mask fixes that on contact. It gives an immediate plump, cushioned feel with deep hydration that actually lasts. Texture is silky, and it looks luxe on its own or under lipstick. High quality, worth the price.
Youth Ritual, “Botox-like” results with patience
If you’re chasing that firmer, smoothed, lifted look many aim for with injectables, this ritual gets you there gradually. Give it time and be consistent, the skin looks more refined, bouncier, and more even week after week. For me, it’s the healthy, non-invasive path to that result.
We’re glad you’re already noticing the difference. That’s exactly what we aim for.
Amazing product!
Thank you!
A hidden gem
Thank you — we’re truly delighted it feels perfect for you.
The youth stem cells ritual completely revitalized my skin, it feels firmer, smoother, and more resilient. The products work perfectly together, giving hydration that lasts even in harsh heat. Expensive, but absolutely worth it for visible results.
We appreciate your recognition — every detail was chosen to meet the highest standards.
